![Why does ring opening reaction (of lactones) often follow nucleophilic pathway and not electrophilic? Why does ring opening reaction (of lactones) often follow nucleophilic pathway and not electrophilic?](https://www.researchgate.net/profile/Md-Imteyaz-Alam/post/Why_does_ring_opening_reaction_of_lactones_often_follow_nucleophilic_pathway_and_not_electrophilic/attachment/59d62923c49f478072e9c151/AS%3A272467027791893%401441972609852/image/El+RO1.jpg)
Why does ring opening reaction (of lactones) often follow nucleophilic pathway and not electrophilic?
![Catalytic upgrading of α-angelica lactone to levulinic acid esters under mild conditions over heterogeneous catalysts - Catalysis Science & Technology (RSC Publishing) DOI:10.1039/C5CY00446B Catalytic upgrading of α-angelica lactone to levulinic acid esters under mild conditions over heterogeneous catalysts - Catalysis Science & Technology (RSC Publishing) DOI:10.1039/C5CY00446B](https://pubs.rsc.org/image/article/2015/CY/c5cy00446b/c5cy00446b-s3_hi-res.gif)
Catalytic upgrading of α-angelica lactone to levulinic acid esters under mild conditions over heterogeneous catalysts - Catalysis Science & Technology (RSC Publishing) DOI:10.1039/C5CY00446B
![Table 4 from Mechanisms of lactone hydrolysis in neutral and alkaline conditions. | Semantic Scholar Table 4 from Mechanisms of lactone hydrolysis in neutral and alkaline conditions. | Semantic Scholar](https://d3i71xaburhd42.cloudfront.net/8b57fe7d6a5984cbeb43a275161918f8d7fa73b5/8-Table4-1.png)
Table 4 from Mechanisms of lactone hydrolysis in neutral and alkaline conditions. | Semantic Scholar
![Mechanisms of Lactone Hydrolysis in Neutral and Alkaline Conditions | The Journal of Organic Chemistry Mechanisms of Lactone Hydrolysis in Neutral and Alkaline Conditions | The Journal of Organic Chemistry](https://pubs.acs.org/cms/10.1021/jo400258w/asset/images/medium/jo-2013-00258w_0013.gif)
Mechanisms of Lactone Hydrolysis in Neutral and Alkaline Conditions | The Journal of Organic Chemistry
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Molecules | Free Full-Text | Mechanisms of a Cyclobutane-Fused Lactone Hydrolysis in Alkaline and Acidic Conditions
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Molecules | Free Full-Text | Mechanisms of a Cyclobutane-Fused Lactone Hydrolysis in Alkaline and Acidic Conditions
![Why does ring opening reaction (of lactones) often follow nucleophilic pathway and not electrophilic? Why does ring opening reaction (of lactones) often follow nucleophilic pathway and not electrophilic?](https://www.researchgate.net/profile/Eric-Harris-6/post/Why_does_ring_opening_reaction_of_lactones_often_follow_nucleophilic_pathway_and_not_electrophilic/attachment/59d63193c49f478072ea11d1/AS%3A273625876238350%401442248900395/image/lactone+2.jpg)
Why does ring opening reaction (of lactones) often follow nucleophilic pathway and not electrophilic?
![Mechanisms of Lactone Hydrolysis in Neutral and Alkaline Conditions | The Journal of Organic Chemistry Mechanisms of Lactone Hydrolysis in Neutral and Alkaline Conditions | The Journal of Organic Chemistry](https://pubs.acs.org/cms/10.1021/jo400258w/asset/images/large/jo-2013-00258w_0011.jpeg)
Mechanisms of Lactone Hydrolysis in Neutral and Alkaline Conditions | The Journal of Organic Chemistry
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